Easy Traditional Chinese Medicine (TCM) Analysis with GC/MS/MS : Choosing the right liner for improved productivity in complex TCM matrices

This presentation summarizes the performance comparison of three popular gas chromatograph (GC) inlet liners for the analysis of pesticides from Traditional Chinese Medicine (TCM). A total of 35 pesticides were chosen for the study in Danshen root (Salvia miltiorrhiza) matrix. A QuEChERS sample preparation method was used to extract target analytes from the matrix. An Agilent 8890 GC, utilizing a mid-column backflush configuration, coupled with an Agilent 7000D Triple Quadrupole mass spectrometer (GC/TQ) was used for the analysis.

The analytical performance of the Agilent Ultra Inert splitless single taper liner with glass wool, the Agilent Ultra Inert splitless dimpled 2 mm ID liner, and the Agilent Ultra Inert splitless single taper liner with frit were examined using the average target response and recovery to identify the best choice of liner for enhanced lab productivity.

Presenter: Siji Joseph (Solution Scientist, Agilent Technologies, Inc.)

Siji Joseph has over 24 years of Analytical experience in food, pharma, and clinical research segments. Siji joined Agilent in 2007, as an Application Scientist in supporting various products like LC, GC, SQ, TQ, QTOF, and spectroscopy products. In his current job title as a Solution Scientist, Siji is working on advanced analytical workflow solution development using Agilent state-of-the-art instruments. Siji Joseph holds a Masters Degree in Analytical Chemistry (Mahatma Gandhi University, India, 1998)